论文摘要
目的 多频听觉稳态反应（multiple auditory steady-state response,MASSR）及短音诱发听性脑干反应（tone-pip evoked auditory brainstem response,Tp-ABR）对听力正常青年人听阈评估的探讨。 方法 对听力正常青年人28名（56耳）,采用MASSR及纯音测听记录0.5、1、2、4kHz阈值,并记录0.5、1、2、4kHz Tp-ABR反应阈及Ⅰ、Ⅲ、Ⅴ波潜伏期及波间期,主观听阈。结果通过统计学软件SPSS11.5进行相关分析。 结果 ①MASSR反应阈左右耳无显著性差异（P>0.05）;0.5kHz较其它有显著性差异（P<0.001）,1、2、4kHz三个频率间无显著性差异（P>0.05）。MASSR反应阈与纯音听阈在0.5、1、2、4kHz各频率两者差值分别为13.9±5.8、10.3±4.7、10.2±3.9、8.1±4.5dB SPL,相关系数分别为0.71、0.83、0.86、0.87。②Tp-ABR反应阈0.5kHz处有显著性差异（P<0.001）外,1、2、4kHz三个频率均无显著性差异（P>0.05）。0.5、1、2、4kHz各频率Tp-ABR反应阈与纯音听阙在两者差值分别为23.8±5.8、20.1±6.6、14.6±4.1、15.6±5.2dB,相关系数分别为0.63、0.75、0.88、0.74,主观听阈与纯音听阈差值分别为20.0±5.1、17.1±5.5、13.8±4.9、13.6±4.1dB nHL。Tp-ABR波间期及潜伏期随频率增加递减。③MASSR反应阈,Tp-ABR反应阈0.5kHz处均有显著性差异（P<0.001）,1、2、4kHz三个频率均无显著性差异（P>0.05）。0.5、1、2、4kHz各频率MASSR反应阈与Tp-ABR反应阈分别为34.6±7.9、24.2±7.6、25.5±7.5、26.7±7.9 dB SPL;31.0±7.8,26.3±8.7,22.1±7.5、21.3±7.1 dB nHL,Pearson相关系数分别为0.69、0.85、0.87、0.81。click-ABR反应阈与MASSR反应阈、Tp-ABR反应阈0.5、1、2、4kHz均值、1、2、4kHz均值、2、4kHz均值Pearson相关系数分别为0.71、0.76、0.85、0.67、0.72、0.88,前者无显著性差异,后者click-ABR反应阈与Tp-ABR反应阈2、4kHz均值Pearson相关系数有差异。（P<0.05）。 结论 MASSR与Tp-ABR均具有频率特异性,两者反应阈与纯音听阈各频率有一定相关性,特别是1、2、4kHz较好。两者均可用于评估纯音听阈。两者各有其优缺点,可结合应用提高临床诊断效能。
论文目录
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标签：多频听觉稳态反应论文; 听性脑干反应论文; 听阈论文;