苏炜:Synthesis and Cytotoxicity of the First Arene Ruthenium Compound Containing Two Thiosemicarbazone Ligands论文

苏炜:Synthesis and Cytotoxicity of the First Arene Ruthenium Compound Containing Two Thiosemicarbazone Ligands论文

本文主要研究内容

作者苏炜,罗志进,崔浩,唐兆丰,李培源,彭炳华(2019)在《Synthesis and Cytotoxicity of the First Arene Ruthenium Compound Containing Two Thiosemicarbazone Ligands》一文中研究指出:A Ru-arene compound containing two thiosemicarbazone ligands [(η6-p-cymene)Ru(TSC)2 Cl]Cl(1, TSC = benzophenone 4-methylthiosemicarbazone) has been synthesized and characterized by 1 H NMR, elemental analysis and HR-ESI mass spectrometry analysis. The molecular structure was determined by single-crystal X-ray diffraction analysis. The in vitro anticancer activities of the complex have been evaluated against two human cancer cell lines(SGC-7901, BEL-7404), and the IC50 values are 32.5 and 57 μM, respectively.

Abstract

A Ru-arene compound containing two thiosemicarbazone ligands [(η6-p-cymene)Ru(TSC)2 Cl]Cl(1, TSC = benzophenone 4-methylthiosemicarbazone) has been synthesized and characterized by 1 H NMR, elemental analysis and HR-ESI mass spectrometry analysis. The molecular structure was determined by single-crystal X-ray diffraction analysis. The in vitro anticancer activities of the complex have been evaluated against two human cancer cell lines(SGC-7901, BEL-7404), and the IC50 values are 32.5 and 57 μM, respectively.

论文参考文献

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  • 论文详细介绍

    论文作者分别是来自Chinese Journal of Structural Chemistry的苏炜,罗志进,崔浩,唐兆丰,李培源,彭炳华,发表于刊物Chinese Journal of Structural Chemistry2019年09期论文,是一篇关于,Chinese Journal of Structural Chemistry2019年09期论文的文章。本文可供学术参考使用,各位学者可以免费参考阅读下载,文章观点不代表本站观点,资料来自Chinese Journal of Structural Chemistry2019年09期论文网站,若本站收录的文献无意侵犯了您的著作版权,请联系我们删除。

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