本文主要研究内容
作者刘瑞来,齐小宝,赵瑨云,付兴平(2019)在《PLLA/PVP纤维三维多孔支架的制备及细胞相容性研究》一文中研究指出:以四氢呋喃(THF)/水为共溶剂,在无其它添加剂条件下,通过低温淬火、萃取、洗涤和干燥得到PLLA/PVP纤维三维多孔支架。采用扫描电镜探讨THF/H2O比例、聚合物浓度、PLLA/PVP比例和淬火温度等条件对纤维支架形貌影响,通过水接触角、吸水率和体外生物活性等测试考察PVP添加对亲水性和生物活性影响。实验结果表明,纤维是由PLLA结晶所形成。PVP加入影响了PLLA结晶,但提高了纤维支架的亲水性。最佳的实验条件为THF/H2O=90∶10、聚合物浓度9%(wt)、PLLA/PVP=90∶10、淬火温度-10℃,得到了直径为270±73nm均一、规整的纤维三维多孔支架,支架的吸水率、孔隙率和比表面积分别为17.29%、96.36%和13.45m2/g,该孔隙率和比表面积为细胞的粘附、迁移、分化、增殖以及养料的传输提供了很好的条件。
Abstract
yi si qing fu nan (THF)/shui wei gong rong ji ,zai mo ji ta tian jia ji tiao jian xia ,tong guo di wen cui huo 、cui qu 、xi di he gan zao de dao PLLA/PVPqian wei san wei duo kong zhi jia 。cai yong sao miao dian jing tan tao THF/H2Obi li 、ju ge wu nong du 、PLLA/PVPbi li he cui huo wen du deng tiao jian dui qian wei zhi jia xing mao ying xiang ,tong guo shui jie chu jiao 、xi shui lv he ti wai sheng wu huo xing deng ce shi kao cha PVPtian jia dui qin shui xing he sheng wu huo xing ying xiang 。shi yan jie guo biao ming ,qian wei shi you PLLAjie jing suo xing cheng 。PVPjia ru ying xiang le PLLAjie jing ,dan di gao le qian wei zhi jia de qin shui xing 。zui jia de shi yan tiao jian wei THF/H2O=90∶10、ju ge wu nong du 9%(wt)、PLLA/PVP=90∶10、cui huo wen du -10℃,de dao le zhi jing wei 270±73nmjun yi 、gui zheng de qian wei san wei duo kong zhi jia ,zhi jia de xi shui lv 、kong xi lv he bi biao mian ji fen bie wei 17.29%、96.36%he 13.45m2/g,gai kong xi lv he bi biao mian ji wei xi bao de nian fu 、qian yi 、fen hua 、zeng shi yi ji yang liao de chuan shu di gong le hen hao de tiao jian 。
论文参考文献
[1].PLLA/PCL复合纳米纤维三维多孔支架的制备及细胞相容性研究[J]. 林皓,刘瑞来,齐小宝,胡家朋,赵瑨云,付兴平.  高分子通报.2019(06)[2].Polyether-polyester and HMDI Based Polyurethanes:Effect of PLLA Content on Structure and Property[J]. Lei Shi,Ruo-Yu Zhang,Wu-Bin Ying,Han Hu,Yu-Bin Wang,Ya-Qian Guo,Wen-Qin Wang,Zhao-Bin Tang,Jin Zhu.  Chinese Journal of Polymer Science.2019(11)[3].Preparation of PLLA/bpV(pic) Microspheres and Their Effect on Nerve Cells[J]. 林强,陈海云,李皓莘,蔡杨庭.  Journal of Huazhong University of Science and Technology(Medical Sciences).2014(01)[4].In vitro Characterization of PBLG-g-HA/PLLA Nanocomposite Scaffolds[J]. 廖岚,YANG Shuang,Richard J Miron,WEI Junchao,ZHANG Yufeng,张萌.  Journal of Wuhan University of Technology(Materials Science Edition).2014(04)[5].A New Route for Preparation of β-TCP/ PLLA Composite[J]. Feng ZHANG1,4, Fang MEI2, Xin Zhi WANG1, Xiao Yang HU1, Yong Ming LUO3, Xu Liang DENG1 1 School and Hospital of Stomatology , Peking University, Beijing 100081. 2Department of Histology and Embryology, Health Science Center, Peking University, Beijing 100083 3Department of Environmental Science and Engineering, Kunming University of Science and Technology, Kunming 650093 4 The 2nd Hospital of Beijing Armed Police Forces, Beijing 100037.  Chinese Chemical Letters.2006(06)[6].PLLA/PCL共混纤维的力学性能研究[J]. 马调调.  橡塑技术与装备.2019(20)[7].Interaction of Human Fibroblasts with Electrospun Composites Gelatin/PLLA,Chitosan/PLLA and PLLA Fibrous Scaffolds[J]. 李建波,韩君,任杰.  Journal of Shanghai Jiaotong University(Science).2012(05)[8].Research of Osteo-induced Rat Mesenchymal Stem Cells Seeding onβ-TCP/PLLA Porous Composite[J]. Qiao-Feng WU~1 Yan-Juan TANG~1 Huai-Qing CHEN~(1△) Jiang WU~1 Guang-Fu YIN~21(Institute of Biomedical Engineering, West China Medical Center of Sichuan University, Chendu 610041,China)2(Institute of Material Science and Engineering, Sichuan University, Chendu 610065,China).  生物医学工程学杂志.2005(S1)[9].PLLA/CS-g-PCL电纺纤维膜的制备及结构性能表征[J]. 刘波,邹黎明,许永静,孙虹,彭显扬.  合成纤维工业.2018(03)[10].热处理时间对PLLA/PDLA纤维结构及性能的影响[J]. 朱爽,韩克清,黄爽,孙旭鹏.  合成纤维.2019(06)
论文详细介绍
论文作者分别是来自高分子通报的刘瑞来,齐小宝,赵瑨云,付兴平,发表于刊物高分子通报2019年04期论文,是一篇关于聚乳酸论文,聚乙烯吡咯烷酮论文,多孔支架论文,热致相分离论文,细胞相容性论文,高分子通报2019年04期论文的文章。本文可供学术参考使用,各位学者可以免费参考阅读下载,文章观点不代表本站观点,资料来自高分子通报2019年04期论文网站,若本站收录的文献无意侵犯了您的著作版权,请联系我们删除。
标签:聚乳酸论文; 聚乙烯吡咯烷酮论文; 多孔支架论文; 热致相分离论文; 细胞相容性论文; 高分子通报2019年04期论文;
刘瑞来:PLLA/PVP纤维三维多孔支架的制备及细胞相容性研究论文
下载Doc文档