论文摘要
目的：观察现有疾病证候检验指标对患者动脉狭窄度的相关性影响及贡献度大小,探索动脉狭窄患者证型的判别方法,以便提高诊断治疗水平。方法：选择做过冠状动脉造影（CAG）的冠心病心绞痛病历450份,然后筛选出经冠状动脉造影（CAG）证实病人有动脉狭窄的病历300份。首先运用DPS软件和SPSS16.0软件对此300份病历资料做出统计处理,然后再从该300份病历中选出分别单独诊断为中医痰浊证和瘀血证的病历各23份,运用SPSS16.0软件对该46份病历资料做出统计处理。结果：分别运用DPS软件和SPSS16.0软件对300份冠心病斑块资料做出统计处理后,得出两种冠心病患者动脉狭窄度与现有疾病证候指标相关性的数学模型；运用SPSS16.0软件对选出的分别单独诊断为中医痰浊证和瘀血证的病历各23份做出统计处理后,得出4个冠心病动脉狭窄患者证候判别的数学模型。结论：1.动脉狭窄度与现有疾病、中医证候及检验指标等因素之间相关性的数学模型可表达为：Y1=+0.502463-0.0842772A1-0.42230381+0.1810334C1一0.1493934D1+0.355276E1+0.3110895F1-0.2627022G1-0.2877669H1一0.67595511+0.551385J1+0.2494212K1+0.785921K2 +0.1583821L1+0.364643L2一0.1772500M1-0.476111M2+ 0.2548246N1+0.516060N2+0.60866301+0.069845302+0.0409897P1+0.2771606P2+0.60052P3+0.5251867P4-0.083998Q1 +0.098608Q2+0.1797728Q3+0.423878Q4+0.2470704R1+0.2011621R2+0.9329229R3+0.7786512R4（用DPS软件处理后得出）Y2=-0.728+0.084X1+0.422X2-0.181X3+0.149X4+0.355X5 +0.311X6+0.263X7+0.288X8+0.676X9+0.551X10-0.249X11 +0.536X12-0.158X13+0.206X14-0.299X15+0.177X16-0.255X17 +0.261X18+0.539X19-0.070X20+0.041X21+0.277X22+0.525X23 +0.601X24+0.084X25+0.183X26+0.264X27+0.508X28+0.201X29+0.247X30+0.779X31+0.933X32。（用SPSS软件处理后得出）2.冠心病动脉狭窄患者证候类型判别的数学模型表达2.1标准化典则判别函数式可以写为：分类=1.018X2+0.458X3-0.426X6-1.603X8-0.275X12+0.875X14 +0.154X16-0.691X17+0.245X18-0.311X19+1.215X20+0.359X21 +1.012X22-0.811X23+1.619X24+0.227X25+0.450X26+1.719X27 +1.590X28-0.219X29+0.016X30-0.624X31-1.426X33.2.2非标准化典则判别函数为：辩证分型=2.081X2+1.609X3-0.909X6-4.110X8-0.541X12+1.921X14 +0.344X16-2.078X17+0.581X18-0.646X19+3.339X20+1.052X21 +2.132X22-1.871X23+3.860X24+0.904X25+1.045X26+3.967X27 +3.278X28-0.568X29+0.036X30-1.599X31-3.400X33-2.766.2.3 Fi sher线性判别函数：瘀血证=-6.609X2+2.334X3+5.164X6-1.523X8+9.819X12-2.042X14+0.170X16+1.617X17+0.298X18+5.894X19-4.146X20 +21.546X21+25.791X22+25.306X23+24.380X24+15.689X25 +11.797X26+13.624X27+4.491X28+8.293X29+13.004X30+1.496X31+4.611X33-23.904;痰浊证=6.138X2+12.190X3-0.403X6-26.698X8+6.504X12+9.723X14 +2.275X16-11.114X17+3.855X18+1.937X19+16.306X20+27.993X21+ 38.850X22+13.843X23+48.022X24+21.229X25+18.195X26+37.921X27 +24.570X28+4.814X29+13.224X30-8.297X31-16.216X33-40.849.