论文摘要
目的:通过分析子宫内膜癌临床病理资料,探讨影响子宫内膜癌预后的因素。方法:对112例在我院住院治疗的子宫内膜癌患者的临床病理资料进行回顾性分析。采用Cox比例风险回归模型研究与预后相关的临床病理学指标,以及治疗方法与生存期和局部复发的关系。结果:初始治疗为手术治疗的子宫内膜癌患者112例,总的生存率为87.1%。接受术后辅助化疗、放疗的病例,高危组明显高于中危组( P < 0.05),中危组明显高于低危组(P < 0.05),差异有显著性。Cox模型单因素分析显示,是否绝经、组织学类型、细胞学分级及高危因素与子宫内膜癌的局部复发有关,而肌层浸润深度、宫颈侵犯与否及是否绝经和总体存活有关。Cox多变量回归分析显示,细胞学分级、组织学类型与子宫内膜癌的复发有关,宫颈是否侵犯与总体存活有关。结论:子宫内膜癌预后良好,应系统评估患者预后因素,实行个体化的治疗方案,以取得更好的疗效。
论文目录
相关论文文献
- [1].Preoperative markers for the prediction of high-risk features in endometrial cancer[J]. World Journal of Clinical Oncology 2020(06)
- [2].Clinical significance and role of up-regulation of SERPINA3 expression in endometrial cancer[J]. World Journal of Clinical Cases 2019(15)
- [3].Function and clinical significance of SUMOylation in type Ⅰ endometrial carcinoma[J]. Oncology and Translational Medicine 2017(06)
- [4].MiR-200a and miR-200b target PTEN to regulate the endometrial cancer cell growth in vitro[J]. Asian Pacific Journal of Tropical Medicine 2017(05)
- [5].Seeking for endometrial carcinoma-related genes and their bioinformatics analysis[J]. 广西医科大学学报 2017(07)
- [6].Clinicopathological Significance of Increased ZIC1 Expression in Human Endometrial Cancer[J]. Journal of Huazhong University of Science and Technology(Medical Sciences) 2015(06)
- [7].The diagnostic value of tumor abnormal protein and high sensitivity C reactive protein in screening for endometrial cancer with endometrial thickness less than 8 mm[J]. Oncology and Translational Medicine 2016(04)
- [8].Screening and diagnosis of endometrial cancer in Lynch syndrome[J]. World Journal of Obstetrics and Gynecology 2016(04)
- [9].Fertility sparing management of endometrial complex hyperplasia and endometrial carcinoma[J]. World Journal of Obstetrics and Gynecology 2014(02)
- [10].Expression of matrix metalloproteinase-7 and tissue inhibitor of metalloproteinase-2 in human endometrial carcinoma[J]. 生殖医学杂志 2010(S2)
- [11].Effect of PDGF-Rb antagonist imatinib on endometrial injury repairing in mouse model[J]. Asian Pacific Journal of Tropical Medicine 2015(07)
- [12].Adenovirus-mediated PTEN gene transfection suppresses growth and promotes chemosensitivity of endometrial carcinoma[J]. Journal of Medical Colleges of PLA 2010(04)
- [13].Quality of life of patients with endometrial cancer undergoing laparoscopic international federation of gynecology and obstetrics staging compared with laparotomy: a Gynecologic Oncology Group study.[J]. 中国肿瘤临床 2010(02)
- [14].Diagnosis and treatment of endometrial carcinoma[J]. Chinese-German Journal of Clinical Oncology 2008(03)
- [15].Expressions of claudin-4 and claudin-1 in endometrial cancer and their significance[J]. Journal of Medical Colleges of PLA 2008(03)
- [16].PTEN coding product:a new marker for tumorigenesis and progession of endometrial carcinoma[J]. 现代妇产科进展 2008(10)
- [17].Correlation between TAMs and proliferation and invasion of type endometrial carcinoma[J]. Asian Pacific Journal of Tropical Medicine 2015(08)
- [18].Correlation between single nucleotide polymorphisms of 17β-HSD-1 and endometrial adenocarcinoma[J]. 现代妇产科进展 2011(08)
- [19].Correlation between PTEN Expression and PI3K/Akt Signal Pathway in Endometrial Carcinoma[J]. Journal of Huazhong University of Science and Technology(Medical Sciences) 2009(01)
- [20].Network pharmacology-based prediction and verification of the mechanism for Bushen Chengyun granule on low endometrial receptivity[J]. Journal of Traditional Chinese Medical Sciences 2020(01)
- [21].Metastatic low-grade endometrial stromal sarcoma with sex cord and smooth muscle differentiation: A case report[J]. World Journal of Clinical Cases 2019(02)
- [22].Apoptosis and endometrial receptivity: Relationship with in vitro fertilization treatment outcome[J]. World Journal of Obstetrics and Gynecology 2016(01)
- [23].Oral malignant acanthosis nigricans associated with endometrial adenocarcinoma[J]. International Journal of Oral Science 2014(04)
- [24].Calcium potentiates the effect of estradiol on PGF2α production in the bovine endometrium[J]. Journal of Animal Science and Biotechnology 2015(02)
- [25].ABO blood type is associated with endometrial cancer risk in Chinese women[J]. 癌症 2011(11)
- [26].Sojucktang induces apoptosis via loss of mitochondrial membrane potential and caspase-3 activation in KLE human endometrial cancer cells[J]. Chinese Science Bulletin 2009(23)
- [27].Cigarette smoking and the risk of endometrial cancer:A meta-analysis[J]. 南京医科大学学报(自然科学版) 2008(07)
- [28].Identification of novel Lynch syndrome mutations in Chinese patients with endometriod endometrial cancer[J]. Cancer Biology & Medicine 2020(02)
- [29].Human adult stem cells from menstrual blood and endometrial tissue[J]. Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2012(05)
- [30].Effect of artesunate on human endometrial carcinoma HEC-1B cells[J]. Journal of Medical Colleges of PLA 2010(03)